麦克白将军(迈克尔·法斯宾德 Michael Fassbender 饰)是苏格兰国王邓肯(大卫·休里斯 David Thewlis 饰)的表弟,在外抵御外敌平反谋乱,战功赫赫,某日归国途中,遇见了三个女巫,女巫预言麦克白将会加官进爵,此言令麦克白心中蠢蠢欲动。然而,最终将要继承王位的,却是班柯将军(帕迪·康斯戴恩 Paddy Considine 饰)的儿子。在妻子(玛丽昂·歌迪亚 Marion Cotillard 饰)的怂恿之下,麦克白杀死了国王,登上了王座,为了保住王位和弑君的秘密,麦克白的双手沾满了鲜血,班柯将军、麦克德夫夫人(伊丽莎白·德比齐 Elizabeth Debicki 饰)和她的孩子均死在了麦克白的屠刀之下,而麦克白亦在疯狂的道路上渐行渐远。
Macbeth, the Thane of Glamis, receives a prophecy from a trio of witches that one day he will become King of Scotland. Consumed by ambition and spurred to action by his wife, Macbeth murders his king and takes the throne for himself.